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19th Sep 2023

FAQs About Supplement Interactions

Posted by Melanie Winter

There is a common misconception that because herbs and vitamins are “natural”, they won’t interact with medications. In reality, as more people use prescription medicines alongside supplements, the potential for interactions becomes more important to consider.

Many people may be taking medications such as blood thinners, statins, or medicines for blood sugar or blood pressure. While these medicines play an important role in managing health, it is essential not to stop or change them without medical advice.

Before starting any new supplement, it is always recommended to check with your doctor or naturopath.

1. Can I take supplements with blood thinners?

Blood thinning medications are used to reduce the risk of blood clots. These include anticoagulants and antiplatelet medicines, commonly prescribed for cardiovascular conditions, post-surgery care, or clotting disorders.

Examples include:

  • Aspirin
  • Warfarin (e.g. Coumadin, Marevan)
  • Heparin
  • Apixaban (Eliquis)
  • Rivaroxaban (Xarelto)

Some foods and supplements may influence blood clotting processes. These can include:

  • Garlic, ginger, and alcohol
  • Fish oil and vitamin E
  • Ginkgo, curcumin, and CoQ10

Warfarin in particular is known to have a higher potential for interactions and requires regular monitoring through blood tests (INR).

Can I take supplements with statins?

Statins are used to help manage cholesterol levels by affecting how cholesterol is produced and cleared by the body.

Common statins include:

  • Atorvastatin
  • Rosuvastatin
  • Simvastatin

Some supplements may influence how statins are processed in the body. For example:

  • St John’s wort may reduce statin effectiveness
  • Magnesium or antacids may affect absorption (especially with rosuvastatin)
  • Red yeast rice should not be combined with statins without supervision

Spacing supplements away from medications (e.g. by a couple of hours) may help minimise interactions.

3. Can supplements interact with diabetes medication?

Some medications, such as metformin, may affect nutrient levels over time. For example, long-term use of metformin has been associated with reduced vitamin B12 levels.

Certain supplements may also influence blood sugar levels, including:

  • Chromium
  • Ginseng
  • Ginkgo
  • Glucosamine

Because of this, monitoring and professional guidance are important when combining supplements with diabetes medications.

4. What about blood pressure medications?

Some blood pressure medications can affect electrolyte balance, particularly potassium levels.

Taking additional potassium through supplements may not be appropriate for everyone. Some supplements, including certain forms of glucosamine, may also contain potassium.

Herbal ingredients may also have additive effects, so it’s important to check suitability with a healthcare professional.

5. Should I stop supplements before surgery?

Some supplements may influence bleeding or interact with anaesthesia.

Common examples include:

  • Fish oil
  • Garlic
  • Ginkgo
  • Vitamin E

It is generally recommended to discuss all supplements with your healthcare provider prior to surgery.

6. When is the best time to take supplements?

Timing can influence both comfort and absorption:

  • Take supplements at least 2 hours away from prescription medications where possible
  • Take B vitamins and zinc with food to reduce nausea
  • Take oil-based supplements (e.g. fish oil, vitamin D, CoQ10) with meals

Key Takeaways

  • Supplements and medications can interact
  • Timing and dosage can influence absorption and tolerance
  • Individual responses vary
  • Professional guidance is recommended before starting new supplements

    Important Information

    Always read the label and follow the directions for use.
    If symptoms persist, talk to your health professional.
    Dietary supplements may interact with medications. Always seek advice from your doctor, pharmacist or qualified healthcare professional before starting new supplements, particularly if you are taking prescription medicines.

    References

    • myDr. Cholesterol treatments for high cholesterol
    • Drugwatch. Blood thinners and cardiovascular health
    • National Institutes of Health (NIH), Office of Dietary Supplements. Frequently Asked Questions
    • Verywell Health. Supplements you should avoid mixing

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